Quick Google search found a couple relevant documents. First one is about gamma in general, second is about changing your display's gamma with a tool built into Windows 7. http://msdn.microsoft.com/en-us/library/windows/desktop/jj635732(v=vs.85).as... Several different API exist for setting the gamma, and if I'm reading this correctly it only "sticks" if an app is full screen and only for the duration of that app? That's probably how it works in the public API, but I bet for Windows tools it can be set more permanently. http://windows.microsoft.com/en-us/windows7/calibrate-your-display This details how to set your display's gamma during the calibration process using Windows 7's software display calibrator. You could use that on each display to determine whether or not the graphics card is capable of setting multiple gamma tables (for multiple displays), just set it to something obviously wacky and see if it sticks.